The drug "Neurobeks": instructions for use, composition, description, reviews

How should I take Neuroeks medication? The instruction on the use of this preparation is described in detail in the materials of this article. Also, it presents patient feedback about the medication, indications, side effects and contraindications.

Composition, form, types of medicinal product and its description

In what form is the drug "Neurobex" sold? The instruction says that such medicine is produced in the form of capsules, pink dragees or biconvex tablets. Their main substances are the following: thiamine nitrate, cyanocobalamin and pyridoxine hydrochloride. Also, the formulation includes auxiliary components in the form of lactose monohydrate, wheat starch, povidone, magnesium stearate, talc and silica colloidal dioxide.

Are there any variants of the "Neurobeks" vitamin complex? Instruction for use informs us that the drug in question is being manufactured in several forms. Let's consider them in more detail:

• "Neurobeks" (contains vitamin B1 - 15 mg, vitamin B6 - 10 mg, and vitamin B12 - 0.02 mg).
• "Neurobeks Forte . " Instructions for use indicate that this form of the drug has an enhanced composition. It contains vitamin B1 (100 mg), vitamin B6 (200 mg) and vitamin B12 (300 mg).
• Neurobeks Neo . Instructions for use of this version of the drug says that it contains vitamin B1 (50 mg), vitamin B6 (200 mg), vitamin B12 (300 mg), vitamin B2 (25 mg), calcium pantothenate, ascorbic acid and folic acid .

General information about the medicine

What is Neurobex? Instruction, expert reviews indicate that this is a combined remedy, which contains vitamins of group B.

The effect of this medication is due to its composition. Consider the properties of the drug in more detail.

Pharmacological properties of the combined agent

Once in the human body, thiamin begins to immediately undergo phosphorylation processes. As a result, cocarboxylase is formed, which is a coenzyme of various enzyme reactions. This component is necessary for performing fat, protein and carbohydrate metabolism, as well as for conducting synapses of nerve impulses.

When there is a shortage of vitamin B1 in the human body, pyruvic and lactic acids accumulate. Subsequently, it can lead to beriberi disease, polyneuritis, Wernicke's encephalopathy, Korsakov's syndrome, impaired cardiac function, polyneuropathy and damage to the digestive tract.

Pyridoxine is extremely important for the normal functioning of the central nervous system. The phosphorylated form of this component is a coenzyme of metabolic processes of enzymes and amino acids that function in the nerve tissues.

In addition, the substance under consideration takes an active part in the biological synthesis of neurotransmitters (i.e., noradrenaline, dopamine, adrenaline, GABA, serotonin and histamine).

The reason for lack of vitamin B6 in the human body can serve as a source of absorption in the digestive tract, malnutrition, as well as taking medications (eg, antagonists) with radiation therapy. Signs of deficiency of this element are seborrheic lesions around the eyes and nose, glossitis, stomatitis, peripheral neuritis, convulsive conditions and anemia.

Cyanocobalamin takes part in the process of hematopoiesis, and also promotes the full maturation of red blood cells. Thanks to vitamin B12, important bioreactions occur in the human body, which ensure its vital activity (the synthesis of nucleic acids and protein, the transfer of methyl groups, the exchange of carbohydrates, amino acids and lipids).

Cyanocobalamin directly affects the work of the nervous system. It produces DNA, RNA, myelin and so on. As for coenzyme forms of this substance (methyl cobalamin and adenosylcobalamin), they are necessary for replication and cell growth. With a lack of vitamin B12 in the body, there are undesirable consequences that affect the work of the hematopoiesis and the nervous system.

Pharmacokinetic parameters of the vitamin complex

Where is the drug "Neurobeks" absorbed? Instructions for use states that the absorption of pyridoxine and thiamine is carried out from the upper intestine. In this case, the medicinal substances are evenly distributed in the body.

The degree of absorption of the drug directly depends on the dose taken.

Cyanocobalamin is absorbed in the upper intestine, as well as in the stomach. In tissue, this substance is transported through the protein of transcobalamin II.

Vitamins of group B, which are part of the medicament under consideration, are metabolized in the liver.

The excretion of pyridoxine and thiamine from the body is carried out by means of the kidneys. At higher doses - through the intestines. As for cyanocobalamin, its excretion occurs together with bile, and a small part with kidneys.

Indications for use of a vitamin preparation

At what diseases the patient can be appointed such a combined drug, as "Neurobeks"? Instructions for use, reviews of experienced doctors say that such a medicine is often used for the complex treatment of the following diseases:

• Chronic circulatory failure, myocardial dystrophy, myocarditis, cardiovascular diseases;
• Asthenic syndrome, spastic conditions of the central genesis, chronic fatigue syndrome, radiculitis, vegetative-vascular dystonia, polyneuritis, encephalopathy, sciatica, osteochondrosis, neuritis, myasthenia gravis, neuralgia, traumatic lesions of the central nervous system and others;
• Circulatory disorders in the retina, optic neuritis, myopia, amblyopia, astigmatism, macular degeneration, glaucoma, diabetic retinopathy, cataract;
• Diabetes mellitus and its complications, thyroid disease, obesity, metabolic disorders of the hormones of the pituitary-hypothalamic system;
• Neurodermatitis, dermatitis of various origins, eczema, acne, shingles;
• Mastopathy, menstrual cycle disorders, conservative therapy of uterine fibroids, endometritis, salpine oophoritis, sensorineural hearing loss, hormonal contraception;
• Neuritis of the auditory nerve, labyrinthopathy;
• Antibiotic treatment, alcoholism, chronic diseases, advanced age, diet;
• Diseases of young children (diathesis, paratrophy, hypotrophy, child developmental lag, school disadaptation syndrome, intensive growth period, infantile cerebral palsy, recovery from infectious diseases).

Contraindications to the use of B vitamins

What are the prohibitions to use Neurobex tablets? The instruction of this preparation says that it is not recommended to take it at:

• Erythrose;
• Acute thromboembolism;
• High sensitivity to the substances included in the composition;
• Erythremia.

The drug "Neurobeks": instructions for use

The tablets "Neurobeks" are intended for the treatment of adults and children from two years of age.

According to specialists, adult patients need to take 2-3 tablets three times a day. For children 10 years of age, the daily dose is 1 tablet three times a day. Babies 5-10 years are assigned 1 tablet twice a day. As for children 2-5 years old, they are given 1 tablet once a day.

Treatment with this drug is a fairly long time (about 2-3 months).

The medicine must be taken at the same time or immediately after a meal. In this case, dragees, tablets and capsules can not be broken or chewed.

Cases of overdose

What are the symptoms when taking higher doses of Neurobeks, Neurobeks Neo, and Neurobeks Forte? The instruction for these drugs states that in patients with overdose, nervous excitement, tachycardia and pain in the heart region may develop.

When observing such symptoms, the affected person is washed with a stomach, and also gives activated charcoal and performs symptomatic therapy.

Side effects

When taking Neurobeks, patients may develop allergic reactions, such as urticaria and pruritus. In addition, nausea and tachycardia are possible.

Drug Interactions

Now you know for what purposes such drugs as Neurobeks, Neurobeks Neo and Neurobeks Forte can be prescribed. Instruction for use states that use of these drugs should only be for the purpose of an experienced doctor. This fact is due to the fact that the drug in question may negatively affect the intake of other medicines.

So, consider the drug interaction of the complex Neurobex:

• Simultaneous reception of this drug with oral contraceptives can reduce the vitamin B6 content in the body.
• An active substance, such as pyridoxine, has a different effect on the metabolism of drugs. In addition, it reduces the antiparkinsonian effect of "Levodopa".
• Pyridoxine antagonists are represented by compounds such as hydralazine and cycloserine. The combination of vitamin B6 and these substances lowers the neurological effect of these drugs.
• Vitamin B6 antagonists include isoniazid and thiosemicarbazone. It was found that pyridoxine positively affects the condition of people with sideroblastic anemia
• Deficiency of vitamin B6 can occur with long-term treatment with penicillamine.
• During the period of taking the drug, it is necessary to refrain from using other multivitamin complexes, which include vitamins of group B.

It should also be noted that the joint use of alcohol-containing medicines and drinks with "Neurobeks" can significantly reduce the absorption of thiamine in the human body.

Analogues of the multivitamin complex and its price

Now you know what the Neurobex is. The instruction of this remedy states that it should be taken only as directed by the doctor. If for any reason you do not have access to the medication in question, you can replace it with similar drugs. In addition to Neurobeks Forte and Neurobeks Neo, they include the following medicines: Aevit, Cytoflavin, Milgamma, Neurorubin, and others.

How much is the Nerobeks vitamin complex? The instruction on this account does not give any information. You can find out the cost only in pharmacies. As a rule, the price of the medicine in question varies between 330-360 rubles.

Opinion about the medicine

Most reviews about the drug "Neurobeq" leave the representative of the weaker sex. As practice shows, it is among women that this vitamin complex enjoys the greatest popularity. Usually it is taken by those who want to improve the condition of their body (nails, hair).

Most people note the high efficacy of the drug in question, but this is only if they complete a full course of therapy with additional calcium, zinc, vitamins A and C. Many women undergo treatment with Neurobex at least twice a year.

There are many reviews on the use of this drug after a complicated disease. In many cases, therapy is highly effective.

It should also be noted that there are many patients who do not have the faintest idea of how the Neurobex is different from its varieties (Neurobeks Forte and Neurobeks Neo). According to specialists, the main difference between these funds is their composition. An intensified and new form of the drug is not recommended for pregnant women and children up to fourteen years of age.