The drug "Barol 20": instructions for use, description, composition and reviews

Modern people suffer more and more often from various diseases of the digestive tract. This is due not only to poor nutrition, but also to the quality of consumed foods, a sedentary lifestyle, as well as poor ecology and the intake of all kinds of medications.

A stomach ulcer or a gastritis will surprise no one today. Moreover, such diseases occur not only in adults and the elderly, but also in young children. That is why many pharmaceutical companies produce various drugs that help restore the gastric mucosa and normalize the digestive tract as a whole.

Very often to treat such conditions patients are prescribed a drug "Barol". The instruction, composition, application of this medication will be described below.

Composition, packaging, description and form of release

In what form are manufactured such a drug as "Barol"? Annotation, the reviews report that the drug under consideration goes on sale in the form of white and blue capsules, which are packaged in blisters and packs of heavy paper, respectively.

Active ingredient of this medication is rabeprazole sodium. NPS, talc, hypromellose, sodium hydrogide, magnesium carbonate, macrogol, titanium dioxide, copolymer methacrylic acid, as well as red and black iron oxides and purified water are used as additional components.

Pharmacological characteristics

How does the drug "Barol 20" (capsules) work? The instruction, the description of the medicine indicate that the drug has antisecretory and antiulcer effects.

According to specialists, this medication is a class antioxidant drug that does not show anticholinergic action. In addition, he does not have the properties of H2 histamine receptor antagonists. It should be noted that "Barol" (price, consumer reviews will be presented below) depresses gastric secretion. As a result, gastric H + and K + adenosine triphosphatases, located on the secretory surface of parietal cells, are suppressed.

Among other things, the drug in question is an inhibitor of the gastric proton pump.

The action of this agent results in the blocking of the final stage of acid secretion. After taking the capsules, they are accumulated and protonated, and also transformed to active sulfenamide.

The antisecretory effect of the drug occurs 60 minutes after its oral administration. It should also be noted that taking the first dose of medication leads to a moderate-inhibitory effect.

Kinetics of the drug

What kinetic properties are inherent in the capsules "Barol"? The instruction and the description of the drug report that this drug is characterized by bioavailability equal to 50%.

The consumption of food, especially greasy, delays the absorption of the active ingredient on average by four hours. However, this fact has no significant effect on its therapeutic effect.

Communication of the drug with plasma proteins is 96%. In the course of metabolism, such components as sulfone and thioether are formed. They have a significant antisecretory effect.

Drug withdrawal occurs mainly through the kidneys.

Indications

What diseases effectively treats the drug "Barol 20"? Instructions for use (the price of this medication is not very high) indicates that this remedy is well manifested when:

• Reflux gastroesophageal disease;
• An ulcer of the 12-colon and stomach;
• Zollinger-Ellison syndrome.

It should also be noted that this medication is often prescribed for eradication Helikobakter Pilori in combination with antibacterial agents.

Contraindications

Are there any contraindications to the drug "Barol 20"? Instruction for use informs you that in no case should such capsules be used when:

• Pregnancy;
• Hypersensitivity to the drug;
• Under the age of 15;
• Breastfeeding.

The drug "Barol 20": instructions for use

Analogs of this tool will be presented at the end of the article.

According to the instruction, the capsules in question are intended for oral administration. For various violations, they are taken one at a time. Duration of treatment is determined only by the doctor.

In the presence of gastroesophageal reflux disease, this drug is used for one capsule for 4-8 weeks. If there are no improvements, then a re-therapy is possible.

As a maintenance treatment, the daily dose of this drug is 10-20 mg.

With symptomatic therapy medication is prescribed in an amount of 10 mg once a day for 4 weeks.

For the treatment of Zollinger-Ellison syndrome, "Barol 20" is recommended to take in a dose equal to 60 mg (the initial daily dosage). At the discretion of the doctor, the indicated amount of the drug can be divided into two doses.

The daily dose of the medicine for the treatment of ulcer of the 12-colon is 20 mg. In this case, the drug should be taken for a month.

Often, this medication is administered within a year. In this case, the maximum single dose of the drug should not exceed 60-120 mg per day.

Adverse events

What side effects does the drug "Barol 20" cause? Instructions for use indicate that this drug often causes such undesirable effects as abdominal pain, nausea, constipation, vomiting, diarrhea, flatulence, dyspepsia and a feeling of dryness in the mouth.

Sometimes, when taking medication, the patient has headaches, asthenia, dizziness, chills, sleep problems, respiratory depression, changes in body temperature, rashes on the skin, and so on.

Signs of an overdose

What are the symptoms of an overdose of Barol 20? Instruction for use states that no such cases have occurred. However, experts do not exclude the possibility of increasing adverse reactions.

In this case, treatment is performed in the form of gastric lavage.

Interaction with other medicines

With what preparations it is forbidden to combine capsules "Barol 20"? Instructions for use inform that rabeprozol can significantly reduce the secretion of hydrochloric acid. This affects the kinetic parameters of drugs, the absorption of which directly depends on the acidity of the gastric juice.

It was also found that the medication in question reduces the concentration in the blood of "Ketoconazole" and increases the content of "Digoxin". In this regard, the simultaneous administration of these drugs requires special control by the attending physician (if necessary, then a dose adjustment is performed).

In general, the drug in question is characterized by a rather low interaction with other drugs.

Special Recommendations

Before the appointment of the drug "Barol" for the treatment of various diseases of the gastrointestinal tract, it is necessary to conduct a medical examination of the patient in order to exclude the presence of oncological disease. This is due to the fact that taking this medication can hide symptoms of serious pathology.

The medicament in question is not prescribed during the period of breastfeeding, since there is no information about the penetration of its active substance into the mother's milk.

In severe disorders in the work of the kidneys and liver, careful medication is required.

The drug "Barol" does not adversely affect a patient's ability to drive vehicles or work with other dangerous mechanisms.

If there are any changes on the skin, the medication should be stopped.

Storage, shelf life and leave at pharmacies

The drug "Barol" is released in pharmacies without a doctor's prescription. However, using it without consulting a doctor is highly discouraged. Otherwise, it can aggravate the patient's already difficult situation.

Contain this medication preferably in a dark, inaccessible to children and dry place, where the air temperature does not exceed 26 degrees. The shelf life of the capsules is two years from the date of manufacture. At the end of this period, use of medicines is prohibited.

Cost and similar preparations

The price of antiulcer is about 215 rubles. If required, it can be replaced with one of such drugs as Veloz, Rabimak, Pariet, Rabelok, Rabeprazol, and Rabizol. The prescribed remedy should only be given by an experienced physician, based on analysis and medical examination data.

Feedback from consumers and doctors

Now you know the properties and characteristics of the drug "Barol 20". The instruction and analogues of the preparation were also presented above.

Reviews about this tool can be found are committed different. Most patients confirm its high efficiency.

Specialists have found that for many drugs that were created on the basis of rabeprazole, a characteristic action is immediate. In this case, there is no need to apply high dosages of the drug or increase the frequency of its use.

It should also be noted that the drug "Barol" is quite good tolerance. It successfully suppresses the secretion of hydrochloric acid.

The medication in question can be prescribed for almost any violations that are indications for its use. For example, it helps quite well during reflux treatment. However, some patients argue that other drugs of a similar action did not always help them.

In combination with antibiotic agents, such capsules are often prescribed for peptic ulcer therapy. This gives highly positive results.

A lot of people with the feeling of "increased acidity" begin to independently choose for themselves various drugs for its treatment. Quite often for these purposes use capsules "Barol". Some consumers argue that this remedy has significantly improved their condition. Although it did not help other patients. Experts argue that the reason for the ineffectiveness of this medication lies in the fact that the aforementioned discomfort is associated with other abnormalities in the work of the digestive tract, which require appropriate therapy. Therefore, it is very important to contact a doctor in a timely manner who, after a medical examination, will give you an accurate diagnosis and prescribe the right treatment.