Ointment "Meloksikam": instructions, analogues, reviews

Disease joints - the problem of a huge number of people of different ages. Help to cope with the pain is helped by medications in the form of tablets, capsules, gels. Ointment "Meloksikam" - one of such means.

Non-steroidal anti-inflammatory drugs

Drugs that help to cope with a particular pain, the pharmaceutical industry is produced a huge amount. They can all be divided into several groups. One of the main - non-steroidal anti-inflammatory drugs (drugs), an abbreviation for their designation - NSAIDs, NSAIDs.

Non-steroidal anti-inflammatory medicinal substances - such an expanded name indicates the difference between this group of drugs and glucocorticoids (steroids), which not only have the same properties as NSAIDs, but also have numerous side effects on the human body, most often unfavorable and unnecessary.

The NSAID group is quite numerous and is used to eliminate heat, pain, inflammation in various organs and tissues in many diseases. "Мелоксикам" - относится именно к таким лекарственным средствам. Ointment "Meloksikam" - refers specifically to such medicines.

Active substance meloxicam

In the pharmacy windows there are sections allocated to non-steroidal anti-inflammatory drugs, among which you can easily find "Meloksikam" ointment. The instruction of this preparation contains all the necessary information about it. So, active active substance served as the name of the drug itself - meloxicam.

It is a derivative of the enolic acid of the group of oxycam. For the first time such substances were synthesized and started to be studied for medical purposes in the middle of the 20th century in the laboratories of the German pharmaceutical company Pfizer. At first it was piroxicam, possessing good anti-inflammatory properties, but having an aggressive effect on the gastrointestinal tract up to bleeding.

The next derivative of oxicam in the 90s of the 20th century was developed by meloxicam. This substance is also an active anti-inflammatory non-steroid agent, but has much less adverse effects on the intestines and kidneys. The meloxicam-based cell has found its application in medicine for the treatment of many diseases and the removal of pain syndrome.

How does meloxicam work?

Ointment "Meloksikam" has a fairly simple mechanism of action through complex processes occurring in the human body. It suppresses the enzyme cyclooxygenase (COX), which through the chain of transformations is responsible for the development of the inflammatory process, the appearance of pain and fever.

But since meloxicam suppresses COX, the effects caused by cyclooxygenase are reduced. At the same time, these mechanisms cause the development of side effects in the gastrointestinal tract, broncho-pulmonary and urinary systems. Science is constantly looking for new ways and means to reduce the level and frequency of side effects of any medicines. And the discovery of meloxicam significantly reduced the occurrence of these problems.

One of the forms, the active element of which is this substance, is "Meloksikam ointment." Instructions for use of this medication describes the possible adverse effects of its use, but they do not happen as often as when using NSAIDs containing piroxicam.

When is meloxicam used?

Nonsteroidal anti-inflammatory drugs have a complex effect on the body - they eliminate inflammation and, as a result, reduce pain and lower body temperature. Due to the fact that meloxicam belongs to this group of drugs, it easily penetrates into body fluids and tissues, passing through histohematological protection, it is used in the treatment of many diseases both independently and in combination with other substances.

As it was found out as a result of conducted clinical trials, meloxicam easily penetrates into the synovial (articular) fluid, its concentration there is 2.5 times higher than in the blood plasma. It is due to this that the substance is actively used in the therapy of the joint apparatus in degenerative-dystrophic processes.

Indications for the use of medications with meloxicam are:

• Ankylosing spondylarthrosis - destruction of intervertebral joints;
• Osteoarthritis - a disease of the joints, the result of which is their destruction;
• Polyarthritis of various origin - inflammatory diseases of the joints, affecting several of them simultaneously;
• Reactive arthritis - recurrent inflammation of the joints, based on the infectious-allergic process, as a result of an earlier infectious disease of the genitourinary or intestinal sphere;
• Rheumatoid arthritis is an inflammatory joint disease that most often arises as an autoimmune manifestation of the instability of the body's condition.

Drugs with meloxicam, including ointment based on meloxicam, whose names can be specified in the nearest pharmacy, actively relieve pain, swelling, fever in various joint diseases.

Features of use

Nonsteroidal anti-inflammatory drugs, which include meloxicam, are available in several dosage forms:

• gel;
• Injections;
• ointment;
• pills.

The methods of application depend on the form of release. In general, meloxicam has the ability of heteroenteric recirculation, that is, getting into the liver from the blood, it is excreted into the intestine, reabsorbed and penetrates into the blood, where it again finds itself in the liver. This process can take from 3 to 5 days. On the basis of this, all dosage forms of meloxicam should be used only once a day. From the body this substance is excreted in the form of metabolites through urine and feces.

The tablet form of meloxicam, which is manufactured by pharmaceutical companies, contains 7, 5 or 15 mg of active substance. This is a therapeutic dose, sufficient for a single daily application on the recommendation of a doctor. Take more than 15 mg of meloxicam per day is not recommended.

Injections of meloxicam are made only by intramuscular injection. Introduce this non-steroidal anti-inflammatory drug intravenously categorically impossible!

Preparations that are used for external use, such as "Meloksikam" ointment, gel, are applied directly to the skin above the affected joint, gently rubbing for several minutes. Hand after the application of the medicine should be thoroughly washed.

If something went wrong

All non-steroidal anti-inflammatory drugs, used to date in clinical practice, to some extent have a side effect on the human body. Most often it manifests itself in the violation of the gastrointestinal tract. It can be:

• Abdominal pain;
• nausea and vomiting;
• flatulence;
• constipation;
• diarrhea;
• Exacerbation of gastric ulcer;
• In rare cases, gastric bleeding;
• In rare cases of liver damage.

Also among the side effects that may appear against the background of taking medications with meloxicam, it should be noted allergic reactions in the form of redness of the skin, itching, irritation of the skin, manifested by alopecia, hyperhidrosis, photodermatosis.

Also, headaches, dizziness, unsteadiness of mood, insomnia can develop. For NSAIDs meloxicam, in comparison with other similar drugs, is most typical, as an adverse reaction, bronchospasm, Quincke's edema, conjunctivitis, and urinary retention.

The development of adverse reactions to taking medications with meloxicam requires immediate treatment of the treating doctor for the elimination of symptoms and correction of the course of treatment.

When can not you apply meloxicam?

Absolute majority of drugs have contraindications for use, depending on the characteristics of the action of the active substance on the patient's body. Here and ointment "Meloksikam", as well as other medicines with this component, can not be taken for treatment in the following cases:

• Bleeding and hemorrhages in the history, especially with gastrointestinal diseases;
• bronchial asthma;
• Inflammatory diseases of the digestive tract;
• "Aspirin triad" - complex presence of bronchial asthma, polyposis of nose and paranasal sinuses, intolerance of acetylsalicylic acid and preparations of pyrazolones group;
• Intolerance of meloxicam or other NSAIDs;
• Severe heart failure;
• Severe renal insufficiency;
• Severe hepatic impairment;
• Bleeding disorders.

Rectal suppositories, in addition to the above, can not be used for inflammatory diseases of the rectum and intestinal anal area, as well as for anal and rectal haemorrhages in the anamnesis.

Children, pregnancy, lactation

Non-steroidal anti-inflammatory drugs, including tablets, injections, suppositories and ointment "Meloxicam", are not recommended for use by children under 15 years of age. Experiments conducted to study the activity of meloxicam, showed that the substance penetrates through the histohematetic barriers.

That is, the placenta for a given substance is not an obstacle to the nascent life. This adversely affects the development of the fetus during pregnancy, and the number of pathologies that can develop as a result of taking medications with meloxicam may be significantly higher than the benefit for the mother in the treatment of joint diseases. That's why pregnant women are strictly forbidden to use meloxicam for the treatment of various diseases.

As for the lactation period, there are no unambiguously verified clinical data. Therefore, breastfeeding women are recommended to stop breastfeeding to undergo treatment with nonsteroidal anti-inflammatory drugs, and meloxicam including, or use other drugs proven and safe for infants receiving breast milk.

During the clinical trials it was found that meloxicam negatively affects fertility (the ability to conceive a child), so medications containing meloxicam should be discontinued several months before the planned pregnancy.

Preparations with an active active ingredient meloxicam are strictly not recommended for use by children under the age of 15, pregnant and breastfeeding women, as well as those men and women who plan to conceive a child in the coming months.

Meloxicam and other medications

One of the NSAIDs, actively used in the therapy of joint diseases, is Meloksikam ointment. Reviews about it are found very different - from laudatory to extremely negative. Meloxicam is one of the active components of many drugs, produced in various forms.

Many pharmaceutical companies in the line of NSAIDs produce an ointment with meloxicam. The names of these funds are different, for example, the widely advertised "Amelotex-gel" or "Matarin" ointment. In many preparations, besides meloxicam, other medicinal substances are contained. The same "Matarin", for example, produced in the form of an ointment, contains a tincture of capsicum, which has a warming and analgesic effect.

The widely known and popular drug "Chondroxide Forte" is a two-component. In it, the main active ingredient is the chondroprotector Chondroitin sulfate, but meloxicam is an additional component that helps fight pain in joint diseases.

Not only "Meloksikam"

The pharmacy network offers a huge selection of non-steroidal anti-inflammatory drugs, the same "Meloksikam" ointment. Analogs of this drug are issued under different trade names. For example, the gel "Amelotex" in its composition contains meloxicam. Its release form promotes greater availability of the active component for the removal of pain and joint treatment, according to some sources, Amelotex delivers up to 99% of the active ingredient to the problem joint for a greater therapeutic effect.

The drug under the trade name "Movasin" also contains meloxicam as the only active substance. But the responses about him are contradictory, many of the patients prefer other similar medications, referring to the fact that "Movsisin" is aggressive and problems with the gastrointestinal tract appear too often when applied.

One of the most frequently asked pharmacies of preparations of the NSAID group with meloxicam is "Movalis", manufactured by the German corporation Boehringer Ingelheim. Patients who note the effectiveness of this drug are satisfied with the low level of side effects when it is used.

First visit to the doctor

Non-steroidal anti-inflammatory drugs containing meloxicam as an active ingredient can be purchased at pharmacies without a doctor's prescription. Analogical drugs are sold in different price categories, which makes them as accessible as possible for patients suffering from joint diseases. But before you get a drug with meloxicam in a drugstore, however, like any other medicine, you should get a doctor's consultation, go through a checkup to know about the illness that caused health problems. Self-medication can not be done!