Nodal periarteritis - what is it?

Perinearthritis is termed systemic vasculitis, a type of artery disease characterized by lesions of the walls of medium and small arteries of inflammatory-necrotic nature. The clinical picture of this disease begins with fever, arthralgia and myalgia. Then there may be such syndromes: neurological, skin, thrombangiotic, cardiac, renal and pulmonary.

In order to confirm nodular periarteritis, morphological examination of skin biopsy specimens is carried out. In the treatment most often used immunosuppressants, corticosteroids and cytostatics. Talk about the severity of the disease can only be after examining the extent of internal organs.

The etiology of this disease is not yet clear. It is believed that nodular periarteritis arises from a viral infection, for example, hepatitis B. Moreover, the stimulant of the disease can be administered serum, vaccination, some medicine, and hypothermia.

The answer to all these factors is the hyperergic reaction. Most often, periarteritis nodosa affects men aged 30 to 50 years.

Nodular periarteritis: classification

The disease is divided into:

1. Classical.
2. Skin-trombangietic.
3. Asthmatic.
4. Mono-organic.

The development of the disease is considered benign, when the cutaneous form of bezvitseropaty is noted. Patients are considered to be socially and physically safe. Their remissions are fairly persistent, but still, exacerbations of vasculitis are not ruled out.

The thrombangiotic variant of the disease is characterized by slow progress. With it, there are often arterial hypertension, microcirculatory disorders and peripheral neuritis.

Relapse of nodular periarteritis arises from the cancellation or lowering of the dose of glucocorticoids, cytostatics, infection, cooling and allergy to medicines.

Allocate such stages of the disease: active, inactive and sclerotic.

In very rare cases, a situation may occur where the nodular periarteritis develops at a lightning speed and causes the patient to die within a year.

Nodular periarteritis: symptoms

If there is a period of exacerbation of the disease, fever, chills, pains in muscles and joints, weight loss and signs characteristic of polyarthritis are observed. Sometimes there may be severe pain in the abdominal region, which is clearly expressed dyspepsia. Also, a common phenomenon with nodular periarteritis - a strong pain in the muscles.

Very characteristic for this disease is kidney damage and the appearance of hypertension, which in some cases becomes malignant. There is a protein in the urine. Quite often the heart can be affected, there may be a myocardial infarction.

In some cases, the disease can begin with a lung injury, bronchial asthma.

If the disease has passed into a chronic form, general symptoms such as polyarthritis and fever may disappear. But instead of them there is a syndrome of defeat of some internal organ. For example, the heart or kidney. Emerging exacerbations can lead to lesions of other organs and systems.

Diagnosis of the disease, based on the defeat of certain organs in combination with fever and chills. In addition, suspicions of this disease can arise due to damage to organs, such as the kidneys, heart or lungs. Critical to the diagnosis is the constant monitoring of the patient. In general, there are no specific, symptom-specific symptoms for this disease. Sometimes the diagnosis can be confirmed by examining a piece of muscle or skin that was obtained from a biopsy.

Now you know what nodular periarteritis is, its treatment should be done only under the supervision of a doctor.