Means of 'Ursofalk'. Reviews. Description. Indications for use

The drug "Ursofalk" is a means of a wide spectrum. The medication has immunomodulatory, hepatoprotective, and also cholelitholytic effect. Drug "Ursofalk" (reviews of experts confirm this) significantly reduces the blood cholesterol.

The active substance of the drug is ursodeoxycholic acid. Some of its amount is contained in human bile. When there are disorders of the liver, the natural level of ursodeoxycholic acid, in connection with a violation of synthesis, is reduced.

The cholesteric effect of "Ursofalk" (the doctors' reviews indicate this) is based on a decrease in the number of hydrophobic acids in the bile, as well as an increase in their secretion into the lumen of the intestine. The drug, in addition, comes into contact with receptors of the ileum. As a result, the absorption of toxic hydrophobic acids decreases.

Drug "Ursofalk" (reviews of many experts confirm this) has a cytoprotective effect. It is related to the ability of the active component of the drug to be "embedded" in the lipid structure of the cell membrane. This helps stabilize and improve the protective properties of the shell.

The drug helps to reduce the synthesis of proinflammatory cytokines.

Due to a decrease in the intestine absorption, and in the liver of cholesterol synthesis, the hypercholesterolemic effect of the Ursofalk is carried out.

The doctors' comments confirm the ability of the drug to reduce the formation and dissolve the existing cholesterol stones. This effect is achieved due to the properties of ursodeoxycholic acid to decrease the lithogenicity of bile as a result of the formation of liquid crystals with the cholesterol molecule.

After ingestion, the active component is absorbed in the small intestine. At the same time in the jejunum and the upper part of the iliac, absorption, based on passive transport, prevails. In the terminal department there is an active transport. About 60-80% of the accepted amount of the drug penetrates into the systemic bloodstream.

Metabolism of the active ingredient occurs in the liver (to a greater extent) and in the intestine (to a lesser extent). Excretion is carried out mainly in the form of metabolites with caloric masses.

The drug "Ursofalk" is prescribed for pathologies of the liver and gallbladder, complicated by cholestasis, an increase in the cholesterol content, a decrease in some hepatic functions. Indications include biliary reflux-gastritis, reflux-esophagitis, liver cirrhosis (primary biliary). The drug "Ursofalk" is prescribed for primary sclerosing cholangitis, hepatitis of various origins (including acute, active chronic, as well as chronic, complicated by cholestasis). The drug is indicated in the presence of cholesterol stones in the gallbladder. In this case, it is allowed to use only if the size of the stones is not more than fifteen millimeters in diameter, and the patient does not have a violation of the gallbladder.

The drug "Ursofalk" is prescribed for cystic fibrosis. Indications include dyskinesia biliary tract, toxic liver damage (including against a background of chronic or acute alcohol poisoning). The drug is prescribed for liver diseases accompanied by cholestasis in children, atresia of the bile intrahepatic ducts.

Assign the drug "Ursofalk" for newborns. The opinions of specialists allow us to conclude that the remedy effectively eliminates prolonged physiological jaundice.

The dosage of the medicine is set individually according to the patient's condition.

It is allowed to take the drug "Ursofalk" during pregnancy. However, the use of medication should be monitored by a physician.

Before applying the drug "Ursofalk" should consult a doctor.