"DuoTrav", eye drops: instructions, indications, use, side effect and feedback

Intraocular called the pressure that occurs between the shell of the eyeball and its contents. Under this term is most often understood the feeling of raspiraniya in the organs of vision and severity in them. With prolonged preservation of this condition, we can talk about the occurrence of such a pathology as glaucoma. It causes increased intraocular pressure.

Blindness is one of the most negative consequences of glaucoma. In this regard, it is so important at the first signs of ailment to seek advice from an ophthalmologist.

Symptoms

As you can see, glaucoma can occur for various reasons. That is why every person should know the symptoms of pathology in order to recognize it in time.

Unfortunately, in the early stages of this insidious disease can absolutely not manifest itself. It happens that a person for a long period does not feel the slightest discomfort. And this happens until the disease does not cause serious damage.

Most people who have eye irritation, their drying and redness, believe that these are just signs of fatigue. In this regard, no measures to correct the situation, they do not accept.

Some people have pain in their eyes. They start to get tired very quickly. There is considerable discomfort and the head starts to hurt. Eyes often turn red. However, the patient still believes this is nothing more than a sign of fatigue.

With the progression of the disease, more serious trouble occurs. The pain in the person's head becomes like a migraine. There is a serious deterioration in vision. Particularly bad people begin to distinguish objects in the dark. Before the eyes often there are circles and fly flies. There is deterioration of the side vision. All these are signs that increased intraocular pressure (symptoms), and treatment should be started immediately. After all, this condition often causes acute attacks. The person has a sharp pain in the head and in the eye, nausea comes.

Diagnostics

If all signs indicate that intraocular pressure (symptoms) is increased and treatment is started immediately, then to effectively eliminate the problem the specialist should establish the reasons for which the pathology has arisen.

The ophthalmologist deals with the diagnosis of the disease. However, the patient will need to go to the reception and to other specialists. This will help to eliminate such causes of glaucoma caused by the pathology of internal organs.

Appointment of eye drops

Eliminate the patient from glaucoma by different methods. Their choice will depend on the stage of the disease. In the absence of irregularities in the functioning of the eye, the simplest means are prescribed. They include themselves:

- regular performance of gymnastics of the organs of vision;
- moistening of the eyes with special drops;
- wearing protective glasses;
- limitation of time spent behind TV and computer;
- refusal from activities associated with constant stress on the eyes;
- the exclusion of occupations in such a sport, in which the likelihood of injury to the organs of vision is high.

A positive impact on the eyes will be light gymnastic exercises and walks, committed in the fresh air.

In addition to these methods, treatment can consist of taking medication and changing lifestyle. The specialist appoints special antiglaucomal drops. Thanks to them, useful substances enter the organs of vision, and fluid outflow occurs.

According to the patients, eyedrops from glaucoma and ocular pressure provide excellent help in the early stages of treatment of pathology. There are a lot of such drugs. However, it is not recommended to purchase them on your own. Self-medication can only cause an exacerbation of the disease. That is why the appointment should contact the ophthalmologist.

Existing drugs

Eye drops from glaucoma and eye pressure are designed to eliminate the symptoms of glaucoma. At the same time, existing drugs reach their goal in various ways. By the mechanism of influence, they are divided into three groups. The first of them includes drops that normalize the pressure in the eyes due to the outflow of fluid and improve blood flow. This group of drugs is also called miotic. It includes several other types of eye drops that differ in their pharmacological action.

Further, there are agents that reduce intraocular pressure while reducing the volume of fluid production.

The third group includes drugs that have a combined effect. They not only reduce the production of liquid, but also improve its outflow.

These drugs include such drugs from glaucoma, as "Fotil", "Proxophilin", "Xalacom" and "Kosopt".

«DuoTrav»

These eye drops belong to the group of myotics. They are a drug that has been developed specifically for the treatment of glaucoma.

What are the active ingredients of DuoTrav (eye drops)? The instruction for its use introduces the composition of this miotik. Its main active ingredients are timolol, as well as travoprost. Due to the first component in the eyes, the production of watery moisture decreases and its outflow is enhanced. All this leads to a decrease in intraocular pressure.

The second substance, travoprost, is a synthetic component. Due to its effect on the organs of vision, the outflow of moisture also occurs and the internal pressure of the eye is actively reduced. However, the synthesis of travoprost does not affect the effect.

After what period of time does the drug "DuoTrav" (eye drops) begin to act? The instruction warns that the effect of using the drug occurs by the end of the 2nd hour after its application. The maximum effect of the drop begins to be about twelve hours later.

How many active ingredients does the composition of the drug "DuoTrav" (eye drops) have? The instruction indicates that 1 ml of the agent includes 40 μg of travoprost and 5 mg of timolol. In addition, some auxiliary substances are also present in the eye drops, namely:

- Е 421 (beckons);
- polyquad;
- boric acid;
Propylene glycol;
- sodium chloride;
- Castor oil;
- sodium hydroxide;
- purified water.

Dosage form and packaging

The drug is an eye drop that belongs to the pharmacological group "Antiglaucoma drugs and miotic remedies".

Prepacked transparent colorless solution in bottles-droppers made of plastic, having a volume of 2.5 ml.

Indications for use

Who is prescribed the drug "DuoTrav" (eye drops)? Instructions for use means that it is recommended for people suffering from IOP (intraocular pressure). It is shown to adult patients with ocular hypertension or open-angle glaucoma, which, judging by the reviews, did not receive the proper effect when treated with analogues of prostaglandins or beta-blockers

Contraindications

Eye drops "DuoTrav" are not used if the patient has:

- bronchial asthma;
- Sinus baricardium;
- heart block;
- a severe form of obstructive pulmonary pathology, which took a chronic form;
- corneal dystrophy;
- chronic heart failure, which is in the stage of decompensation;
- pregnancy;
- lactation;
- cardiogenic shock;
- severe allergic rhinitis.

Contraindicated drops to children, adolescents, as well as individuals who are hypersensitive to the drug.

Pharmacokinetics

The preparation "DuoTrav" allows to normalize the raised intraocular pressure. How does it affect the body? When absorbed through the cornea of the ester of travoprost, which is inherently a prodrug, this substance undergoes a hydrodisation process. As a result, the active form of the acid component acts on the body.

When conducting clinical trials, it was found that the drug has a low systemic effect in terms of severity. Thus, in two of the three examined individuals, the maximum concentration of the agent in the blood plasma was less than 0.01 ng / ml. And this content of the drug was observed only after half an hour after its administration. And only in one of the three examined patients this value reached the value of 0.052 ng / ml.

The process of half-life of the solution from the blood plasma lasts approximately 45 minutes. And after one hour, travoprost can not be determined by laboratory methods available to researchers.

Also, according to clinical trials, the concentration of the active substance of the drug in the blood plasma between the first and seventh day of the course is no different. This indicates that there is no appreciable cumulation and a rapid achievement of the required dose. The metabolism of the drug occurs to inactive elements, which are usually excreted by the kidneys, as well as in the bile.

Dosage

How to instill eyes with the drug "DuoTrav" to adult patients, including elderly people? Dosage for such patients is equal to one drop of the drug, which should fall into the conjunctival sac of the glaucoma-affected eye. The procedure is carried out once a day in the morning or in the evenings. It is only necessary to remember that the use of the drug should occur at the same time. If the procedure was missed, the next day the doubling of the dosage is not required.

Treatment of the affected eye should be performed in strict accordance with the instructions. Do not use more than one drop.

How to instill eyes with the drug, if there are violations in the functioning of the kidneys and liver? Such patients do not need to adjust the amount of the funds.

Overdose

If you get into a conjunctive bag more than one drop, rinse your eyes with water immediately. According to some patients, in such cases they had to suffer from eye irritation, baricardia, lowering blood pressure, eye hyperemia and other side effects. It will take a symptomatic treatment.

Mode of application

To prepare the preparation for the procedure from the bottle, it is necessary to remove the protective packaging. To prevent infection of the solution and the tip of the dropper, take care not to touch any surface with the tip of the bottle.
Before the procedure, you need to remove the protective ring. It is on the vial and is designed to control the first autopsy.

After instillation of the drug, it is necessary to close the eyelids for a couple of minutes or press the area of the nasolacrimal hole. Such actions will reduce systemic side effects and increase local activity of the remedy.

In the case when the ophthalmologist except for the preparation "DuoTrav" has appointed other eye drops, the break in their application should not be less than 5 minutes.

Before using the product, the patient should remove the contact lenses available from him and put them on only after fifteen minutes after the procedure.

Adverse Reactions

Instruction for the use of the drug "DuoTrav" indicates the probability of negative reactions of the body, which can be:

- hyperemia of the eyes;
- Point keratitis;
- blurred vision;
- dry eyes;
- photophobia;
- eye irritation;
- impaired vision;
- erythema eyelids;
- increased lacrimation;
- edema of the eyelids;
- increased eyelash growth.

Extraneous side effects may result in the appearance of angina and chest pain, the occurrence of depressions and disorders of the functioning of the gastrointestinal tract, worsening of the prostate gland and headaches, urinary incontinence and sinusitis.

Similar negative reactions are noted in 1-5 patients out of 100.

Cost of preparation

Of course, a very effective drug for glaucoma is the drug "DuoTrav". The price for it, however, will satisfy not all consumers. In Russian pharmacies, these drops are sold from 700 to 800 rubles per bottle. In this regard, people who have increased intraocular pressure, seek to acquire not "DuoTrav". Analogues of these eye drops are more affordable. In the list of cheaper, but at the same time, judging by the responses of patients, quite effective drugs, are the following:

- "Timolol";
- "Azopt";
- "Kossopt";
- "Travatan";
- "Xalatan";
- "Okumed";
- Fotil.

However, it is worth remembering that the doctor prescribes the "DuoTrav" remedy, and only he can recommend a cheaper analogue to the patient, who will also fight the disease as effectively as this miotic. Independently to change the medicines included in the course of treatment is not recommended.