Capsules "Indap". Instructions for use

The drug "Indap" - antihypertensive agent, acting as a vasodilator and diuretic. The usual form of release of this medication is capsules containing 2.5 mg of indapamide hemihydrate. The drug "Indap" is assigned to reduce high blood pressure in the treatment of hypertension.

The principle of the drug is similar to thiazide diuretics, which, according to the general opinion of physicians around the world, should be present in any scheme for the treatment of hypertension. With regard to the preparation "Indap", the instruction for use indicates that its action is based on a violation of the reverse absorption of sodium ions in the surface area in the Henle loop. Thus, the excretion of magnesium, potassium, sodium and chlorine ions from the body with urine is accelerated. The drug selectively blocks "delayed" calcium channels, reduces peripheral resistance of blood vessels, increases the elasticity of their walls.

Since there is no effect of the drug on carbohydrate metabolism and the amount of lipids in the blood plasma, it can be prescribed to diabetics. However, with such an exacerbation of diabetes, such as ketoacidosis, the drug "Indap", the instruction notes this, do not prescribe.

It is noteworthy that high dosages of this medication cause an increased urinary excretion, but this does not affect the degree of decrease in blood pressure. That is why it is recommended to take the drug "Indap" repeatedly and stably, which will help reduce the pressure, starting from the second week of the course.

The drug "Indap". Instructions for use . Contraindications

As for the obvious contraindications to the use, this list for the drug "Indap" is quite extensive. In particular, this drug is contraindicated in anuria, liver damage, hypokalemia, renal pathology, and indapamide indigestion. Also, it is not recommended to prescribe medication for allergic reaction to lactose, impaired glucose absorption, galactosemia, and cerebral circulation.

For a number of diseases, the preparation "Indap" can be prescribed if the threat of arterial hypertension for the organism exceeds the risks of complications that may arise with certain probability when it is taken. These are ailments such as ascites, mild renal / hepatic insufficiency, water-electrolyte balance disorders, hyperuricemia, hyponatremia, hyperparathyroidism, urate nephrourolythiasis, and gout. The same applies to the period of breastfeeding.

"Indap". Instructions for use . Side effects

The degree of severity of side effects directly depends on the dosage of the drug "Indap". However, the mechanism of interference in metabolic processes, characteristic for the active substance of this drug, has caused the breadth of the spectrum of side effects on various body systems. In particular, there are the following types of side effects of this medication:

• On the digestive system (dyspepsia, pain in the gastrointestinal tract, nausea, dry mouth, stool disorders, vomiting, gastralgia, impaired appetite);
• On the nervous system (nervousness, dizziness, asthenia, headaches, vestibular dysfunction, drowsiness, depression, insomnia, irritability, agitation, anxiety, nervousness, tension, lethargy, asthenia, lethargy, malaise, fatigue, spasm of muscle fibers);
• On the sense organs (conjunctivitis, visual impairment);
• On the respiratory system (pharyngitis, rhinitis, cough);
• On the cardiovascular system (arrhythmias, palpitation, orthostatic hypotension, hypokalemia);
• On the urinary system (nocturia, polyuria, frequent infections of the urinary system).

Also, the side effects of the drug "Indap" include back pain, various infections, flu-like syndrome, pain in the sternum, excessive sweating, violations of libido or potency, numbness and tingling in the extremities, allergy, sudden weight loss, hyperglycemia, hyponatremia, hypochloremia, Hyperuricemia, glucosuria and a number of other metabolic disorders in the body.

Mode of application

If the preparation "Indap" is prescribed, the instructions for use regulate the main time of taking in the morning hours, inward, does not allow an increase in dosage due to the increase in this case the likelihood of side effects and unattainability of the normal blood pressure level. In arterial hypertension, the initial dosage is considered to be 1.25-2.5 mg per day (for non-delayed forms of indapamide), or 1.5 mg (for prolonged forms of indapamide) per day. In case the effectiveness of treatment with the drug is not sufficient, a drug with another mechanism of action should be added to the treatment regimen in 4-8 weeks.