What helps "Furazolidon"? Composition, instruction, analogues of the preparation

Do you know what the drug "Furazolidon" is? From what these pills are appointed by doctors and how to take them? These and other questions will be answered in the materials of this article.

Form of release of the medicinal product, its composition

About what helps "Furazolidon", we will tell below.

According to the instruction, said preparation is made in the form of tablets. Their main component is furazolidone. Also, the drug contains an auxiliary substance such as lactose.

In what packaging is the drug "Furazolidon" sold? Instructions for use (analogues of this product are indicated below) of these tablets are contained in a cardboard bundle. As for the drug itself, it is packaged in cell or cell-free packaging.

Mechanism of action

What helps "Furazolidon"? According to the instructions, it is an antibacterial drug. Its pharmacological action directly depends on the prescribed dosage. When using a small amount of furazolidone, the drug exhibits a bacteriostatic effect. If the dosage of the drug is increased, it has a pronounced bactericidal effect.

Speaking about the drug "Furazolidon" (from which these tablets, we learn below), we can not say that this tool is characterized by some immunostimulating effect.

The antimicrobial effect of the drug in question is explained by the ability of its nitro groups to be reduced to an amino group. This occurs under the action of bacterial enzymes.

The components that were formed during the reduction of the nitro group have a toxic effect. In addition, they block a number of biological and chemical processes in bacterial cells, and also violate the integrity and structure of their shell.

When furazolidone is used, blockade (irreversible) of NADH is observed, as well as inhibition of the tricarboxylic acid cycle. This effect contributes to the disruption of cellular respiration of microorganisms, the work of the cytoplasmic membrane, as a result of which the death of harmful microorganisms occurs.

Features of the tool

Due to the ability of the furazolidone molecule to form complex compounds with nucleic acids, this means disrupts the synthesis of proteins in bacterial cells, thereby inhibiting the multiplication and growth of harmful microorganisms.

What helps "Furazolidon"? This remedy is well manifested with reduced immunity. These properties of the drug are associated with its ability to increase activity (phagocytic) and the complement titre of leukocytes. In addition, the main substance of this agent reduces the production of toxins by bacteria, so that the overall clinical picture improves much earlier than microbiological tests show a negative result.

Properties of the preparation

What properties are characteristic for the drug "Furazolidon"? What helps this tool? Specialists have shown that furazolidone is capable of inhibiting monoamine oxidase. This feature of the drug leads to the development of mild excitation in patients.

Also it should be said that this drug increases the sensitivity of the body to ethanol. This can lead to the development of vomiting and excessive nausea when sharing drugs and alcoholic beverages.

So what helps with "Furazolidon"? This drug is highly effective in the treatment of infectious diseases that are caused by strains of bacteria that are sensitive to the effects of furazolidone. In addition, the said agent is well manifested in the case of protozoa and candida fungi. However, it should be noted that sensitivity tests are necessary before prescribing this medication.

According to the doctors, the medication in question has practically no effect on the pathogens of anaerobic as well as purulent infection.

The drug "Furazolidon": what helps?

Tablets with this name are often used to treat people with infectious diseases in the genitourinary sphere. In addition, they are very effective in the presence of diseases of the digestive tract and skin.

Answering the question about what Furazolidon treats from, you can safely list the following conditions: typhus, bacillary dysentery, food poisoning, paratyphoid, diarrhea of an infectious origin, vaginitis, enterocolitis, urethritis, giardiasis, trichomonas infection, trichomonas colpitis, cystitis, infected Wounds and burns, pyelit.

Prohibitions for taking medication

Are there any contraindications to the tablets "Furazolidone" (it helps very well against cystitis)? According to the instructions, the medicine in question can not be used when:

• Lactase deficiency and lack of glucose-6-phosphotehydrogenase;
• Hypersensitivity (individual) to the components of the drug;
• Renal failure of a chronic type (including in the terminal stage) ;
• At the age of up to one month;
• Breastfeeding;
• Impaired renal function;
• Pregnancy;
• Liver disease and HC;
• Driving and working with dangerous machinery.

Instructions for the use of Furazolidon tablets

It helps very well against the diarrhea. This is due to the fact that it is able to inhibit the growth and multiplication of bacteria that contribute to the development of dysbiosis.

This drug is taken orally. The tablet should be swallowed in its entirety, not crushed and chewed, but only washed down with a large amount of liquid.

The drug should be taken only after a meal. The duration of treatment for them, as well as the dosage of the drug is determined by the treating doctor individually for each patient (depending on the nature of the disease and individual characteristics of the person).

Will Furazolidon help with rumbling in the abdomen? Of course, it will. Adult patients for the therapy of food-borne diseases, paratyphoid and dysentery are prescribed 2-3 tablets of medication four times a day. The duration of the course depends on the severity of the disease and is approximately 5-10 days.

The medicament in question can be used in cycles. In this case, it is prescribed for 0.1-0.15 g four times a day for 3-6 days, after which they make a short break in 3-4 days. Then the medication is renewed according to the same scheme.

For the treatment of giardiasis, this drug is prescribed (adults) to 0.1 g four times a day.

For the treatment of trichomoniasis urethritis, 2 tablets of a drug with the same multiplicity are used. The duration of the course in this case is 3 days.

To treat colpitis trichomonadal adults are recommended to take 0.1 g of medicament three times a day. For better therapeutic effect, the drug in question is combined with drugs that also contain furazolidone, but only in the form of rectal and vaginal suppositories. The duration of the general course of therapy with this drug is 1-2 weeks. In this case, the duration of oral administration of the drug should not exceed three days.

The maximum dosage (single) for adults is 0.2 g, and the daily dosage is 0.8 g.

To children for treatment of food toxic infections, paratyphoid and dysentery the dose of this agent is determined depending on body weight and age. The maximum duration of therapy in this case is 10 days.

To treat giardiasis, children are usually prescribed 10 mg / kg of drug per day. The above amount of the drug is preferably divided into 4 divided doses.

To treat infected burns and wounds, the drug is recommended for use in the form of wet-drying gauze bandages or irrigation. To do this, prepare a solution of furazolidone, the concentration of which will be 1: 25000.

Side effects

According to the instructions, the agent in question is low in toxicity. Although in some cases, against the background of its administration, such side effects may develop, such as:

• Anorexia, skin rash, nausea, urticaria;
• Vomiting, itching, pain in the epigastric region, angioedema.

To reduce the severity of such phenomena, the drug is recommended to be washed down with a large amount of liquid. Also, use antihistamines and B vitamins.

With strongly pronounced adverse reactions, the medication should be discontinued, and then immediately consult a doctor.

With prolonged use of the medication, the patient may develop hemolytic anemia and methemoglobinemia (mainly in newborns and infants). In addition, the drug in question is characterized by such adverse reactions as dyspnea, cough, hyperthermia, and neurotoxic effects.

Overdose with pills

In case of an overdose with this remedy, people suffer toxic liver damage, including acute toxic hepatitis. It is also possible to develop polyneuritis and hematotoxic action of the active substance.

Drug Interactions

With the joint administration of the drug "Furazolidone" with the means that change the pH of the urine, a change in the rate of excretion of its active substance is observed.

With simultaneous use of tetracycline and aminoglycosides enhance the pharmacological effects of furazolidone, and when combined with "Ristomycin" and "Chloramphenicol", the hematopoiesis is inhibited.

When furazolidone is taken with alcohol, disulfiram-like reactions develop.

This drug is not prescribed together with antidepressants, ephedrine, monoamine oxidase inhibitors, tyramine, amphetamine and phenylephrine. This is associated with a risk of developing hypertensive effects.

Analogues and reviews

Replace the drug in question by such means as Betadine, Laktozhinal, Geksikon, Chlorhexidine, Hypozol, Trichomonacid, Dafnejin, Macmiore, Depantol, Yodoxid, Yodovidone ".

Patients' reviews of this medication are mostly positive. They argue that "Furazolidon" manifests itself as a very effective antibacterial drug. It well eliminates the signs of cystitis, and also copes with other problems in the genitourinary sphere and treats dysbiosis.

In addition to positive reports, this drug is left and negative feedback. They say that the tablets "Furazolidon" cause such side effects as vomiting, skin rash, nausea and urticaria.