"Thiamine chloride" - features of application

"Thiamine chloride" is a synthetic preparation of vitamin B1, which refers to water-soluble vitamins and turns into cocarboxylase in the body. And already it is a coenzyme of enzyme reactions. This vitamin takes an active part in protein, as well as fat and carbohydrate metabolism.

"Thiamine chloride" is taken parenterally, so it quickly enters the bloodstream and is then distributed between tissues and organs. The process of phosphorylation occurs in the liver, after which it accumulates in the heart, liver, kidneys, brain, spleen. About 10% of this vitamin is excreted from the patient's body unchanged through the kidneys and liver.

Indications for use of this drug

"Thiamine chloride" is a vitamin, and it is prescribed in the presence of vitamin deficiency or hypovitaminosis B1, as well as for the treatment of radiculitis, encephalopathy, neuritis, peptic ulcer of the stomach, neurasthenia, peripheral paralysis, polyneuritis, peptic ulcer of the duodenum. Also, it is prescribed in the presence of liver diseases, spasms of peripheral vessels, eczema, dermatosis of neurogenic origin, myocardial dystrophy, intestinal atony, neuralgia, psoriasis, pyoderma and skin itching.

"Thiamine chloride" - instruction for use

5% solution of this drug for adults and for children is administered 1 time during the day, the procedure is carried out daily. For children, the daily dose is not more than 0.25 ml, and for adults 1 ml of this solution. Usually the course of treatment with the drug is from 10 to 30 injections.

Possible side effects

The use of the drug "Thiamine chloride" can cause allergic reactions, and sometimes anaphylactic shock. The most susceptible to their occurrence are patients who are prone to allergies, and who have allergic reactions to B group vitamins in the anamnesis.

Contraindications

The drug should not be taken with hypersensitivity, hypertension, as well as in the presence of allergic diseases and idiosyncrasy. Caution should be taken "Thiamine chloride" to people who have increased nervous excitability and hyperacid forms of peptic ulcer of the duodenum.

Do not mix this product with solutions containing sulfites. This leads to the fact that "Tiamin chloride" in them completely disintegrates. It is also not recommended to take this vitamin together with vitamins B6 and B12.

Overdose

If this drug is taken in elevated doses and for a fairly long period of time, then symptoms such as headache, tremor, agitation, insomnia and increased heart rate may develop . Usually, after the withdrawal of this remedy, all these symptoms pass by themselves, but if necessary, it is necessary to carry out symptomatic treatment.

Injections are performed to obtain a more rapid result, as well as to patients who have impaired intestinal function. But it is recommended to start with small doses of the drug, they should not exceed 0.5 ml of a 5% solution, if the drug is well tolerated, then its dose is adjusted to the recommended amount. If the drug is administered intravenously, then it must be done very slowly, and if the muscle is deep, then. Injections can sometimes cause minor pain, which is explained by the low pH of the solution. Alcoholics and women who are in menopausal and premenopausal periods may have increased side effects.

It is not recommended to mix "Thiamine chloride" in one syringe with streptomycin or penicillin, as the antibiotic is destroyed, and also mix it with nicotinic acid, as thiamine is destroyed.