OJSS analysis - what is it?

Our body consists of the most diverse trace elements. All of them are very important for our life. But there is one, the content of which determines a lot: the state of our organs, their work, the quality of blood and, as a consequence, our general condition. Ironically, we are talking about iron. It is involved in providing blood to hemoglobin, therefore, performs a vital function. Iron is not in the body in such a form as it enters there. It enters into chemical reactions, is transported, binds at the expense of other substances, in particular transferrin.

Why do we need transferrin?

When people ask: "OJSS - what is it?", It is important to understand what exactly determines this analysis. This is a test for the content of iron and protein transferrin in the body. This protein plays a key role in supplying the bone marrow with erythrocytes, where a continuous process of formation of new blood cells takes place. It is transferrin that helps saturate them with iron. This protein is very important, because it binds the molecules of iron and carries them through the cellular membranes of the bone marrow. The process of iron saturation is necessary for the normal functioning of human systems and organs.

OZHSS - what is it?

The abbreviation of this analysis stands for "total iron binding ability of the serum." In other words, the analysis shows the concentration of the trasferrin in the body. But it must be remembered that when receiving OJSS results (blood test) this ability can be overestimated to 20%. This is due to the fact that if iron is saturated with transferrin (more than half as a percentage), it can bind to other proteins. Here it should be noted that the results of the analysis show the amount of iron that can and can bind to transferrin.

Why is it necessary to do OJSS analysis?

Speaking about the importance of iron and transferrin in the body, it must be taken into account that this analysis determines not only the indices of binding of one molecule to another. OZHSS - what is it and what do the results of this analysis give us? According to the results of a microbiological study, a specialist can see the dynamics - latent or unsaturated iron-binding capacity. For further treatment or doctor's recommendations, all indicators are important.

Preparation for the analysis, material for it

OJSS analysis - what is it? Knowing the answer to this question, you need to remember the basic requirements for its conduct. Blood sampling is performed strictly on an empty stomach in order to avoid incorrect results. To determine the required index, serum blood is taken . It can be stored in the refrigerator if necessary, but it is better to do the analysis on the basis of fresh biomaterial. The analysis is performed quickly, for 3 hours. Then the results will be ready.

What is the norm of OJSS for adults and children?

The indicators of this analysis differ depending on age. Still need to consider the presence of pregnancy. Many women are frightened at the sight of the results of the analysis and ask specialists: "OJSS is elevated - what does this mean?" But do not prematurely panic, because in this state with a normal pregnancy can occur an increase in the norm OZHSS.

The norm for children is within the following limits:

At the age of 2 years, reference values range from 100 to 400 μg / dL, or from 17.90 to 71.60 μmol / L.

If a child is more than 2 years old, his normal values range from 250 to 425 μg / dL, or from 44.75 to 76.1 μmol / l.

How much is detected in adults with OJSS? The norm in women has such indicators: 38,0-64,0 mcm / l. Men have reference values from 45.0 to 75.0 μm / l.

At what diseases or conditions does this increase?

If OZHSS it is raised, what does it mean? Such deviations from the norm indicate the presence of any pathological processes in the body. Now we will consider them.

Elevated values may indicate the presence of hypochromic anemia - pathology, in which the color index of blood is assessed. It happens when there is a lack of iron in the body. It is easy to get rid of this pathology.

In late pregnancy, too, there may be increased rates of this analysis.

Chronic blood loss changes the content of OJSS in the blood. It is important to stop this process as soon as possible so that a person does not lose vitality.

Acute hepatitis also affects the OJSS figures. This is due to the connection of the indicator with the amount of bilirubin and with the functioning of the liver.

With true polycythemia, there may also be OZSSS elevated. This malignant formation, a disease of the blood, which increases its viscosity. This is due to an increase in the number of red blood cells in the blood. But the platelets and leukocytes also increase in number. Due to the increase in viscosity and the amount of blood in the cells, stagnation is observed, which leads to the formation of thrombi, as well as to hypoxia. At the same time, blood flow suffers, in the tissues of the body do not reach the necessary substances in the right amount.

OZHSS it is raised also can be at a lack of iron in food or its wrong mastering by an organism. In the first case, a special diet is needed, which can balance all the processes. In the second case, a specialist consultation is necessary, since several organs with their hormones and enzymes are responsible for the assimilation of nutrients.

The states under which OWSS is lowered

Of the pathologies in which OZHSS in the blood is less than normal, you need to identify a few particularly dangerous.

1. Pernicious anemia - unsaturation of the body with iron due to lack of vitamin B ₁₂ . This is a dangerous disease, as several systems suffer from it at once.
2. Hemolytic anemia is a pathological process in which decay of erythrocytes occurs due to some internal mechanisms. The disease is rare, not fully understood.
3. Sickle cell anemia is a disease in which the protein of hemoglobin changes at a genetic level. As a result, there is a disruption in the assimilation of iron by the cells and tissues of the body.
4. Hemochromatosis - excessive accumulation of iron in all tissues, organs. This is a genetic disease. It can lead to serious complications, for example, cirrhosis of the liver or diabetes, arthritis and some others.
5. Atransferrinemia is a deficiency in the blood of transferrin protein. Due to this, iron can not get into the necessary bone marrow cells, so the appearance of new red blood cells is blocked. This is a rare genetic disease.
6. Chronic iron poisoning is due to excessive consumption of iron-containing products along with drugs containing iron.
7. Chronic infections can affect organs that are responsible for the supply of red blood cells to cells in the body, and other systems.
8. When nephrosis, decreased rates of OJSS in humans are observed. With this disease, the structure of the kidneys changes, kidney tubular dystrophy occurs.
9. With hepatic insufficiency, the metabolism in cells is disrupted, there is a deficit of erythrocytes.
10. Kwashiorkor (dystrophy) is rare, but with this disease there is also a deficiency of OJSS in the blood. This pathology results from severe dystrophy of the child and even of an adult person due to a lack of protein in the food. Since transferrin and hemoglobin are proteins, on their formation this process also affects.
11. In the presence of malignant tumors, this indicator can also be lowered.

Calculation of the saturation coefficient

Based on the results of the analysis, the doctor can calculate the value, which is called the transferrin saturation coefficient in the body. It is calculated by the formula: 100x (serum iron: OZHSS). There are norms for the coefficient. This range from 16 to 54. But the average value is 31.2. According to this indicator, the doctor draws conclusions about the overall condition of the patient. If necessary, an additional examination is performed, which will show where the patient's health is going badly.