"Corinfar": reviews, prices, instruction manual

"Corinfar" - a medicine that is part of the group of calcium channel blockers. The drug prevents the penetration of calcium ions into the cell membranes, contributes to a decrease in the tone of the vascular walls, so it is often used at elevated blood pressure. The medication has an antianginal effect, due to which coronary insufficiency is successfully treated for ischemic disease. "Corinfar Uno" reviews are reflected as an effective remedy for stopping angina attacks.

The form of the release, the ingredients present in the composition

The drug is available in film-coated tablets. The active ingredient, in which nifedipine is used, is 10, 20 or 40 mg in one tablet.

Auxiliary ingredients are magnesium stearate, potato starch, povidone K25, lactose monohydrate and microcrystalline cellulose are also present.

pharmachologic effect

The hypotensive effect of the drug makes it possible to weaken and make the heart contractions more rare. Such changes in the body lead to a decrease in the need of the heart in oxygen. Coronary blood flow increases after the use of Corinfar. Instructions for use, reviews show that treatment with this drug leads to positive changes in those areas of the myocardium, where blood circulation is disturbed.

The medication begins to act about twenty minutes after ingestion, the effect is saved for an average of five hours. Through the gastrointestinal tract, about 90% of the drug penetrates into the blood, the maximum level of the active substance is reached on average in three hours. The drug is characterized by high bioavailability (from 50 to 70%), which is promoted by food intake, and the connection with plasma proteins (95%). The drug of prolonged forms allows you to save the result for 24 hours.

It is known that during the treatment passes through the natural barriers the drug "Corinfar". The reviews report that the drug can penetrate the placenta and the BBB, is found in breast milk. Metabolism "Corinfar" occurs in the liver. The processes of hydrolysis and oxidation lead to the formation of inactive metabolites, most of which are excreted in the urine, the rest - through the intestines with bile. 1% of the drug is immune to metabolic processes and passes through the kidneys in an unchanged form. Partial elimination of the drug is carried out within two to five hours, with problems with the liver - longer.

Indications

Medication is prescribed for hypertension, as well as for variant angina and angina of stable chronic form (CHD). Indications include Raynaud's disease, colic (intestinal, biliary, renal), bronchial obstructive syndrome, bronchial asthma (complex treatment).

Contraindications

Instruction to the preparation "Corinfar", reviews report that treatment with the use of this drug is prohibited in such cases:

• Hypersensitivity to the components of the agent;
• Cardiogenic shock;
• Myocardial infarction of acute form (the first 4 weeks);
• Low blood pressure - hypotension, at which the systolic pressure drops below 90 mm Hg. P.
• Stenosis arterial (pronounced);
• Angina pectoris (unstable) ;
• Heart failure of chronic form (decompensation stage);
• The initial trimester when carrying a child, breast-feeding.

In cases when it is planned to carry out treatment with the medicine "Corinfar", the reviews recommend caution in identifying such conditions:

• Hepatic failure, renal;
• Hypertension arterial, having a malignant character;
• Intestinal obstruction;
• Pronounced bradycardia, tachycardia;
• Myocardial infarction (especially in cases when left ventricular failure is detected ) ;
• Severe bleeding disorders of the cerebral circulation;
• Stenosis, in which the mitral valve is affected;
• Age less than 18 years or more. 60.

At the time of treatment, it is worth noting grapefruit juice, since after its use, the metabolism of the active component of the drug is disrupted.

Treatment

To eat "Corinfar" reviews, the instruction is recommended after eating, not chewing and using a large amount of water. The dosage of the drug is selected individually, depends on the sensitivity to the components and the patient's condition.

With angina pectoris chronic form is first appointed two or three doses of the drug in a single dose of 10 mg. When obtaining an insufficient effect, an increase in the dose of the drug to 20 mg is permitted. During the day, you can not take more than 40 mg of the drug.

With essential hypertension, the average medication dose required for one day's intake corresponds to two to three 10-mg tablets. At one time you can drink one tablet. A single dose can be increased to two tablets. In a day you can not eat more than four tablets. It is necessary to observe a minimum interval of four hours between each intake of the drug.

Tablets 10 mg

The recommended dosage is one tablet for daily intake of two to three times, if you need an increase in the dose - two tablets at the frequency of application once or twice a day. It is forbidden to use more than 40 mg of medication per day.

Tablets 20 and 40 mg

"Corinfar Retard" reviews and instructions recommend eating twice a day - one or two tablets at a time.

The medicine with a dosage of 40 mg ("Corinfar Uno") should be applied once a day, preferably in the morning, one tablet is enough.

Adverse events

Side effects that can cause the drug with different dosages of the main component include violations in the work of the cardiovascular system and hematopoiesis, urinary system, in the functioning of the liver and digestive tract. Side effects can manifest themselves in the activity of the central nervous system, in the work of the musculoskeletal system. Allergic reactions are possible.

If there is a collapse, there is pain in the chest, the drug is immediately canceled. In cases where the recommended dose is exceeded, myalgia may develop, in rare cases, paresthesia of the extremities was observed, vision was temporarily impaired, and fatigue was present. Long-term treatment sometimes leads to the appearance of gynecomastia in the elderly, to the development of gingival hyperplasia and hyperglycemia. There may be other problems. Usually, for the disappearance of side effects, it is sufficient to cancel the drug.

The cost of the drug, analogues

Recommended for review information are the instructions attached to the preparation "Corinfar", the price, reviews, analogues. Buy medicine (50 tablets) can be an average of 70-85 rubles.

Among the analogs of the drug are Nykardiya, Fenigidin, Nifadil. As a substitute, "Nifelat", "Kalzigard", "Pharmadipin" or "Nifedikap" can be used. Possible treatment with the use of "Nifecard", "Cordipina", "Adalat", "Niefeni", "Nifedipina." To the structural analogues belong "Kordafen", "Cordaflex". To implement the therapy, fit "Nifedikor" and "Nifegeksal".

Reviews

If you plan to start treatment with the drug Corinfar, instructions, price, reviews, analogues allow you to decide on the most appropriate medicine. The reviews show that the drug provides a rapid reduction in blood pressure (for half an hour). The result is noticeable even after a single dose. To reduce the pressure to normal, the doctor must choose the most appropriate dose. Usually, an increase in the dose of the drug is performed if the necessary effect is not obtained, there are no restrictions, and there are no side effects. Buyers like the low price of the drug and the effectiveness of treatment. On side effects in the reviews is not mentioned.