The medicine Orungamin. Instructions for use

The drug Orungamin (tablets) is included in the category of antifungal agents with a wide range of activities. The mechanism of drug effect is based on the ability of the active substance - itraconazole - to inhibit the synthesis process in the membrane of fungal cells. The agent is effective in yeast, yeast-like fungi, dermatophytes. The maximum bioavailability is noted when ingested directly after a dense meal. The drug reaches its highest concentration in three to four hours.

The Orungamin. Instructions for use. Indications

The medicine is prescribed for fungal keratitis, dermatomycosis, onychomycosis, caused by yeast / dermatophytes and moldy mushrooms. Indications include systemic mycoses: candidiasis and aspergillosis, sporotrichosis, histoplasmosis, cryptococcosis (cryptococcal meningitis, among others). Medication "Orungamin" instruction for use recommends for blastomycosis, paracoccidioidomycosis and other tropical or systemic lesions. Assign a remedy for pityriasis, candidomas with spreading to the mucous or skin, vulvovaginal candidiasis including, with deep visceral candidiasis.

The drug Orungamin. Instructions

Testimonials of experts confirm the expediency of taking the medicine immediately after eating. The drug is swallowed whole. In cases of immunity disorders, reduced absorption may be noted. In this connection, the need for an increase in dosage is likely. Against the backdrop of onychomycosis, a "pulse-therapy" is prescribed. One course involves taking a medication in a dose of two tablets / capsules per day twice. Duration of treatment - a week. With fungal nail lesions of the hands, two courses are recommended, legs - three. The break between weekdays is 21 days. As the nails grow, the clinical results will become apparent. Against the backdrop of onychomycosis (according to the severity of the course of the pathology), a specialist can prescribe a continuous intake of the drug for three months, two capsules / tablets per day.

Side effects

When taking the drug, indigestion, toxic liver damage of a serious nature, increased activity of liver enzymes (reversible), constipation, nausea. Patients may have jaundice (cholestatic), anorexia, hepatitis, peripheral neuropathy, headache. In a number of cases, dizziness, hypokalemia, swelling, headache, fatigue occur. For women on the basis of treatment, the menstrual cycle may be impaired. To negative manifestations when taking Orungamin medication, the instruction for use refers to congestive heart failure, darkening of the urine, pulmonary edema, angioedema. The drug also provokes alopecia.

The medicine Orungamin. Instructions for use. Contraindications

Do not prescribe the drug simultaneously with the medications "Midazolam", "Triazolam", "Pimozid", "Quinidine", "Dofetilide", "Cisapride", "Lovastatin", "Simvastatin". Contraindications include intolerance. Appointment for pregnancy / lactation is made according to vital indications.