Medicinal product "Cordinorm". Instructions for use

The drug "Cordinorm", the instruction for use informs, is made in the form of tablets, covered with a film membrane. The international non-proprietary name is bisoprolol.

One tablet contains five milligrams of bisoprolol fumarate, the main active ingredient. Additional constituents are macrogol 6000, microcrystalline cellulose, mannitol, magnesium stearate and titanium dioxide.

Tablets weighing five or ten milligrams are sold on sale. On one side there is a risk and engraving "B5" or "B10". The drug belongs to the pharmacotherapeutic group of selective beta-1 adrenoblockers.

The considered tool "Cordinorm", the instruction informs, provides reduction of myocardial oxygen demand, as well as a reduction in the frequency of cardiac contractions both at rest and during exercise.

The drug is characterized by a high degree of absorption (about eighty to ninety percent), and eating food for absorption is not affected. In addition, the drug penetrates through the placental and blood-brain barrier in minimum volumes. In breast milk is found a small amount.

The period during which the medication is half removed from the body can range from nine to twelve hours. About ninety-eight percent is excreted by the kidneys, the remaining two - with bile.

Pharmaceutical preparation "Cordinorm" instruction prescribes to apply for arterial hypertension, ischemic heart disease, and also for the prevention of angina attacks.

This drug is contraindicated in patients with increased sensitivity to bisoprolol and other components. It is not prescribed for pulmonary edema, cardiogenic shock, collapse, acute or chronic heart failure, severe bradycardia, cardiomegaly, arterial hypotension, bronchial asthma, obstructive pulmonary disease in the chronic stage, simultaneous administration of MAO inhibitors, Raynaud's disease, pheochromocytoma, metabolic acidosis, and Also to persons under the age of eighteen.

The drug "Cordinorm", the instruction emphasizes, with special care is prescribed if the patient suffers from diabetes, myasthenia gravis, thyrotoxicosis, hepatic or renal insufficiency, depression, psoriasis. Older patients taking this medication need constant specialist supervision.

The drug "Cordinorm". Instructions for use

This drug should be used for two and a half to five milligrams at a time. Tablets are taken orally, in the morning before eating, without chewing. The daily volume is, as a rule, 5 mg, if necessary, it can be doubled (according to the recommendation of the attending physician). Elderly patients do not adjust the dose.

Possible side effects: weakness, dizziness, fatigue, headaches, sleep disturbances, nightmares, depression, tremors and some other disorders of the central nervous system. In addition, it is possible to reduce the production of tear fluid, blurred vision, conjunctivitis, dry eyes and mucous membranes of the mouth, abdominal pain, vomiting, nausea, malfunction of the liver. In hypersensitive patients, skin rash, itching, urticaria and other allergic reactions were observed.

Overdose of "Cordinorm", patients' reviews confirm this, accompanied by severe headaches, fainting, convulsions, bronchospasm, difficulty breathing.

It is noted that the simultaneous use of non-steroidal anti-inflammatory drugs and this medication weakens the hypotensive effect produced by the latter.

The drug "Cordinorm" is released only if a prescription is available.